TIZIANA LIFE SCIENCES PLC



Company Documents

DateDescription
22/06/2122 June 2021 Register inspection address has been changed to Link Group 10th Floor Central Sqaure 29 Wellington Street Leeds LS1 4DL

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22/06/2122 June 2021 Register(s) moved to registered inspection location Link Group 10th Floor Central Sqaure 29 Wellington Street Leeds LS1 4DL

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21/06/2121 June 2021 Group of companies' accounts made up to 2020-12-31

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23/07/2023 July 2020 21/07/20 STATEMENT OF CAPITAL GBP 4980242.7

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22/07/2022 July 2020 20/07/20 STATEMENT OF CAPITAL GBP 4954742.7

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22/07/2022 July 2020 17/07/20 STATEMENT OF CAPITAL GBP 4954742.7

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20/07/2020 July 2020 16/07/20 STATEMENT OF CAPITAL GBP 4935692.7

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16/07/2016 July 2020 15/07/20 STATEMENT OF CAPITAL GBP 4933292.7

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16/07/2016 July 2020 15/07/20 STATEMENT OF CAPITAL GBP 4933292.7

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14/07/2014 July 2020 13/07/20 STATEMENT OF CAPITAL GBP 4922027.7

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02/07/202 July 2020 30/06/20 STATEMENT OF CAPITAL GBP 4921277.7

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24/06/2024 June 2020 22/06/20 STATEMENT OF CAPITAL GBP 4918952.7

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17/06/2017 June 2020 ARTICLES OF ASSOCIATION

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17/06/2017 June 2020 ADOPT ARTICLES 06/05/2020

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08/06/208 June 2020 05/06/20 STATEMENT OF CAPITAL GBP 4911452.7

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05/06/205 June 2020 02/06/20 STATEMENT OF CAPITAL GBP 4909952.7

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03/06/203 June 2020 01/06/20 STATEMENT OF CAPITAL GBP 4900952.7

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03/06/203 June 2020 27/05/20 STATEMENT OF CAPITAL GBP 4895702.7

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01/06/201 June 2020 26/05/20 STATEMENT OF CAPITAL GBP 4880702.7

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26/05/2026 May 2020 22/05/20 STATEMENT OF CAPITAL GBP 4906868.58

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21/05/2021 May 2020 19/05/20 STATEMENT OF CAPITAL GBP 4847559.84

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21/05/2021 May 2020 18/05/20 STATEMENT OF CAPITAL GBP 4836459.84

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14/05/2014 May 2020 13/05/20 STATEMENT OF CAPITAL GBP 4829591.34

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13/05/2013 May 2020 12/05/20 STATEMENT OF CAPITAL GBP 4829161.89

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07/05/207 May 2020 05/05/20 STATEMENT OF CAPITAL GBP 4829006.49

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04/05/204 May 2020 23/04/20 STATEMENT OF CAPITAL GBP 4823006.49

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04/05/204 May 2020 23/04/20 STATEMENT OF CAPITAL GBP 4823006.49

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30/04/2030 April 2020 28/04/20 STATEMENT OF CAPITAL GBP 4639442.58

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27/04/2027 April 2020 17/04/20 STATEMENT OF CAPITAL GBP 4631942.58

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27/04/2027 April 2020 22/04/20 STATEMENT OF CAPITAL GBP 4631942.58

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27/04/2027 April 2020 20/04/20 STATEMENT OF CAPITAL GBP 4631942.58

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27/04/2027 April 2020 15/04/20 STATEMENT OF CAPITAL GBP 4631942.58

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24/04/2024 April 2020 15/04/20 STATEMENT OF CAPITAL GBP 4612235.43

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24/04/2024 April 2020 15/04/20 STATEMENT OF CAPITAL GBP 4612235.43

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24/04/2024 April 2020 15/04/20 STATEMENT OF CAPITAL GBP 4612235.43

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14/04/2014 April 2020 16/03/20 STATEMENT OF CAPITAL GBP 4599635.43

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13/02/2013 February 2020 CONFIRMATION STATEMENT MADE ON 11/02/20, WITH UPDATES

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11/02/2011 February 2020 DIRECTOR APPOINTED MR GREGOR CHARLES WILLIAM MACRAE

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31/12/1931 December 2019 GROUP OF COMPANIES' ACCOUNTS MADE UP TO 31/12/19

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12/12/1912 December 2019 19/11/19 STATEMENT OF CAPITAL GBP 4099635.48

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12/12/1912 December 2019 APPOINTMENT TERMINATED, DIRECTOR LEOPOLDO ZAMBELETTI

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19/08/1919 August 2019 CORPORATE SECRETARY APPOINTED ACCOMPLISH SECRETARIES LIMITED

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19/08/1919 August 2019 APPOINTMENT TERMINATED, DIRECTOR RICCARDO DALLA-FAVERA

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19/08/1919 August 2019 APPOINTMENT TERMINATED, SECRETARY PAUL COOPER

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29/07/1929 July 2019 ACCOUNTS RECEIVED/DIRS RE-APP/APP OF AUDITOR/REMUNERATION OF AUDITOR 31/05/2019

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22/02/1922 February 2019 23/11/18 STATEMENT OF CAPITAL GBP 4092294.54

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22/02/1922 February 2019 11/12/18 STATEMENT OF CAPITAL GBP 4093914.54

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20/02/1920 February 2019 CONFIRMATION STATEMENT MADE ON 11/02/19, WITH UPDATES

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15/02/1915 February 2019 CORRECTION OF ALLOTMENT DETAILS OF FORM SH01 REGISTERED ON 14/02/19. SHARES ALLOTTED ON 14/08/17. BARCODE L7YKVR14

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15/02/1915 February 2019 SECOND FILED SH01 - 15/12/17 STATEMENT OF CAPITAL GBP 3751644.15

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14/02/1914 February 2019 SECOND FILING OF CONFIRMATION STATEMENT DATED 11/02/2018

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14/02/1914 February 2019 SECOND FILING OF CONFIRMATION STATEMENT DATED 11/02/2017

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14/02/1914 February 2019 SECOND FILED SH01 - 20/11/18 STATEMENT OF CAPITAL GBP 3959421.54

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14/02/1914 February 2019 SECOND FILED SH01 - 19/11/18 STATEMENT OF CAPITAL GBP 3853273.47

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14/02/1914 February 2019 SECOND FILED SH01 - 27/04/18 STATEMENT OF CAPITAL GBP 3807818.97

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14/02/1914 February 2019 SECOND FILED SH01 - 05/03/18 STATEMENT OF CAPITAL GBP 3807128.55

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14/02/1914 February 2019 SECOND FILED SH01 - 19/01/18 STATEMENT OF CAPITAL GBP 3756644.16

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14/02/1914 February 2019 SECOND FILED SH01 - 15/01/18 STATEMENT OF CAPITAL GBP 3754644.15

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14/02/1914 February 2019 SECOND FILED SH01 - 27/11/17 STATEMENT OF CAPITAL GBP 3723338.13

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14/02/1914 February 2019 SECOND FILED SH01 - 20/11/17 STATEMENT OF CAPITAL GBP 3717838.14

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14/02/1914 February 2019 SECOND FILED SH01 - 14/08/17 STATEMENT OF CAPITAL GBP 3714838.14

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14/02/1914 February 2019 SECOND FILED SH01 - 23/03/17 STATEMENT OF CAPITAL GBP 2885487.75

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31/12/1831 December 2018 GROUP OF COMPANIES' ACCOUNTS MADE UP TO 31/12/18

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27/11/1827 November 2018 19/11/18 STATEMENT OF CAPITAL GBP 10568314.9469

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27/11/1827 November 2018 20/11/18 STATEMENT OF CAPITAL GBP 10568314.9469

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21/11/1821 November 2018 27/04/18 STATEMENT OF CAPITAL GBP 10411312.3769

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02/08/182 August 2018 05/03/18 STATEMENT OF CAPITAL GBP 10410621.9569

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02/08/182 August 2018 19/01/18 STATEMENT OF CAPITAL GBP 10360137.5669

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02/08/182 August 2018 15/01/18 STATEMENT OF CAPITAL GBP 10358137.5569

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02/08/182 August 2018 14/08/17 STATEMENT OF CAPITAL GBP 10318331.5469

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02/08/182 August 2018 23/03/17 STATEMENT OF CAPITAL GBP 9488981.1569

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19/07/1819 July 2018 DIRECTOR APPOINTED MR LEOPOLDO ZAMBELETTI

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03/07/183 July 2018 AUTHORISED ALLOTMENT OF SHARES AND DEBENTURES

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01/03/181 March 2018 CONFIRMATION STATEMENT MADE ON 11/02/18, NO UPDATES

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05/02/185 February 2018 27/11/17 STATEMENT OF CAPITAL GBP 10360637.5469

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23/01/1823 January 2018 20/11/17 STATEMENT OF CAPITAL GBP 10318331.5469

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23/01/1823 January 2018 19/12/17 STATEMENT OF CAPITAL GBP 10355137.5569

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31/12/1731 December 2017 GROUP OF COMPANIES' ACCOUNTS MADE UP TO 31/12/17

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15/08/1715 August 2017 NOTIFICATION OF A PERSON WITH SIGNIFICANT CONTROL GRAEME WALTER BRIGGS

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07/07/177 July 2017 AUTHORISED ALLOTMENT OF SHARES AND DEBENTURES

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13/02/1713 February 2017 CONFIRMATION STATEMENT MADE ON 11/02/17, NO UPDATES

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31/12/1631 December 2016 GROUP OF COMPANIES' ACCOUNTS MADE UP TO 31/12/16

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22/09/1622 September 2016 30/06/16 STATEMENT OF CAPITAL GBP 9435295.4369

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14/09/1614 September 2016 ON CANCELLATION OF SHARE PREMIUM ACCOUNT AND CAPITAL REDEMPTION RESERVE COMPANY NUMBER 3508592 WHEREAS TIZIANA LIFE SCIENCES PL HAVING BY SPECIAL RESOLUTION CANCELLED ITS SHARE PREMIUM ACCOUNT AND CAPITAL REDEMPTION RESERVE AS CONFIRMED BY AN ORDER OF THE HIGH COURT OF JUSTICE CHANCERY DIVISION DATED THE 14TH SEPTEMBER 2016

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14/09/1614 September 2016 ON
CANCELLATION OF SHARE PREMIUM ACCOUNT AND CAPITAL REDEMPTION RESERVE


COMPANY NUMBER 3508592


WHEREAS TIZIANA LIFE SCIENCES PL


HAVING BY SPECIAL RESOLUTION CANCELLED ITS SHARE PREMIUM ACCOUNT AND CAPITAL REDEMPTION RESERVE AS CONFIRMED BY AN ORDER OF THE HIGH COURT OF JUSTICE CHANCERY DIVISION

DATED THE 14TH SEPTEMBER 2016

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14/09/1614 September 2016 STATEMENT OF CAPITAL

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14/09/1614 September 2016 14/09/16 STATEMENT OF CAPITAL GBP 283180203

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08/09/168 September 2016 DIRECTOR'S CHANGE OF PARTICULARS / DR KUNWAR SHAILUBHAI / 15/08/2016

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08/09/168 September 2016 DIRECTOR'S CHANGE OF PARTICULARS / GABRIELE MARCO ANTONIO CERRONE / 15/08/2016

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31/08/1631 August 2016 RETURN OF PURCHASE OF OWN SHARES

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16/08/1616 August 2016 DIRECTOR'S CHANGE OF PARTICULARS / DR RICCARDO DALLA-FAVERA / 15/08/2016

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16/08/1616 August 2016 SECRETARY'S CHANGE OF PARTICULARS / PAUL JOHN COOPER / 15/08/2016

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15/08/1615 August 2016 REGISTERED OFFICE CHANGED ON 15/08/2016 FROM 18 SOUTH STREET MAYFAIR LONDON W1K 1DG

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15/08/1615 August 2016 REGISTERED OFFICE CHANGED ON 15/08/2016 FROM
18 SOUTH STREET
MAYFAIR
LONDON
W1K 1DG

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19/07/1619 July 2016 28/06/16 STATEMENT OF CAPITAL GBP 9435295.4069

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12/07/1612 July 2016 ADOPT ARTICLES 30/06/2016

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17/05/1617 May 2016 28/04/16 STATEMENT OF CAPITAL GBP 9408107.91

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20/04/1620 April 2016 11/02/16 NO MEMBER LIST

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07/04/167 April 2016 SECOND FILING FOR FORM SH01

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16/03/1616 March 2016 APPOINTMENT TERMINATED, DIRECTOR CHRISTOPHER MCGUIGAN

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31/12/1531 December 2015 GROUP OF COMPANIES' ACCOUNTS MADE UP TO 31/12/15

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17/12/1517 December 2015 DIRECTOR APPOINTED WILLY JULES SIMON

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19/11/1519 November 2015 05/11/15 STATEMENT OF CAPITAL GBP 9375257.9069

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29/05/1529 May 2015 APPOINTMENT TERMINATED, DIRECTOR PHILIP BOYD

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29/05/1529 May 2015 APPOINTMENT TERMINATED, SECRETARY PHILIP BOYD

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27/05/1527 May 2015 SECRETARY APPOINTED PAUL JOHN COOPER

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20/04/1520 April 2015 31/03/15 STATEMENT OF CAPITAL GBP 9373511.25

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15/04/1515 April 2015 11/02/15 NO MEMBER LIST

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15/04/1515 April 2015 25/03/15 STATEMENT OF CAPITAL GBP 9271511.25

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26/03/1526 March 2015 APPOINTMENT TERMINATED, DIRECTOR ANDREW GUTMANN

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06/03/156 March 2015 DIRECTOR APPOINTED PROF CHRISTOPHER MCGUIGAN

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06/03/156 March 2015 DIRECTOR APPOINTED DR KUNWAR SHAILUBHAI

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27/02/1527 February 2015 22/01/15 STATEMENT OF CAPITAL GBP 9270671.25

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31/12/1431 December 2014 GROUP OF COMPANIES' ACCOUNTS MADE UP TO 31/12/14

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03/09/143 September 2014 29/07/14 STATEMENT OF CAPITAL GBP 9143662.77

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29/08/1429 August 2014 AUDITOR'S RESIGNATION

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02/07/142 July 2014 SECOND FILING FOR FORM SH01

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01/07/141 July 2014 18/06/14 STATEMENT OF CAPITAL GBP 9142722.78

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30/06/1430 June 2014 CONSOLIDATION 23/04/14

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30/06/1430 June 2014 CONSOLIDATION
23/04/14

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14/05/1414 May 2014 SECRETARY APPOINTED DR PHILIP JAMES BOYD

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12/05/1412 May 2014 DIRECTOR APPOINTED DR RICCARDO DALLA-FAVERA

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12/05/1412 May 2014 DIRECTOR APPOINTED GABRIELE MARCO ANTONIO CERRONE

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12/05/1412 May 2014 DIRECTOR APPOINTED DR PHILIP JAMES BOYD

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09/05/149 May 2014 REGISTERED OFFICE CHANGED ON 09/05/2014 FROM, 6 NEW STREET SQUARE, NEW FETTER LANE, LONDON, EC4A 3BF

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09/05/149 May 2014 AUTHORISED ALLOTMENT OF SHARES AND DEBENTURES

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09/05/149 May 2014 DISAPPLICATION OF PRE-EMPTION RIGHTS

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09/05/149 May 2014 VARYING SHARE RIGHTS AND NAMES

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09/05/149 May 2014 COMPANY BUSINESS 23/04/2014

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09/05/149 May 2014 23/04/14 STATEMENT OF CAPITAL GBP 16570765.68

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09/05/149 May 2014 CONSOLIDATION
23/04/14

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09/05/149 May 2014 CONSOLIDATION 23/04/14

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09/05/149 May 2014 APPOINTMENT TERMINATED, DIRECTOR DAVID SCOTT

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09/05/149 May 2014 APPOINTMENT TERMINATED, DIRECTOR PERCY LOMAX

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09/05/149 May 2014 APPOINTMENT TERMINATED, DIRECTOR CHRISTOPHER ROURKE

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09/05/149 May 2014 APPOINTMENT TERMINATED, SECRETARY NORMAN LOTT

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23/04/1423 April 2014 COMPANY NAME CHANGED ALEXANDER DAVID INVESTMENTS PLC CERTIFICATE ISSUED ON 23/04/14

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23/04/1423 April 2014 COMPANY NAME CHANGED ALEXANDER DAVID INVESTMENTS PLC
CERTIFICATE ISSUED ON 23/04/14

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03/04/143 April 2014 11/02/14

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31/12/1331 December 2013 FULL ACCOUNTS MADE UP TO 31/12/13

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18/07/1318 July 2013 AUTHORISED ALLOTMENT OF SHARES AND DEBENTURES

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18/07/1318 July 2013 RECEIVE & ADOPT DIRECTORS-AUDITORS REPORT-ACCOUNTS/RE-ELECT DIRECTORS/APPOINT AUDITOR/AUTHORISATION 28/06/2013

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24/06/1324 June 2013 11/02/13 NO MEMBER LIST

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12/06/1312 June 2013 REGISTERED OFFICE CHANGED ON 12/06/2013 FROM, 90 FETTER LANE, LONDON, EC4A 1EQ

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12/06/1312 June 2013 REGISTERED OFFICE CHANGED ON 12/06/2013 FROM
90 FETTER LANE
LONDON
EC4A 1EQ

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20/05/1320 May 2013 01/05/13 STATEMENT OF CAPITAL GBP 6663321.83

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09/05/139 May 2013 DIRECTOR APPOINTED ANDREW GUTMANN

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09/05/139 May 2013 DIRECTOR APPOINTED CHRISTOPHER WILLIAM ROURKE

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09/05/139 May 2013 APPOINTMENT TERMINATED, DIRECTOR NORMAN LOTT

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09/05/139 May 2013 APPOINTMENT TERMINATED, DIRECTOR MICHAEL HICKS

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08/03/138 March 2013 DECLARATION OF SATISFACTION IN FULL OR IN PART OF A MORTGAGE OR CHARGE /FULL /CHARGE NO 1

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08/03/138 March 2013 DECLARATION OF SATISFACTION IN FULL OR IN PART OF A MORTGAGE OR CHARGE /FULL /CHARGE NO 4

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08/03/138 March 2013 DECLARATION OF SATISFACTION IN FULL OR IN PART OF A MORTGAGE OR CHARGE /FULL /CHARGE NO 2

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08/03/138 March 2013 DECLARATION OF SATISFACTION IN FULL OR IN PART OF A MORTGAGE OR CHARGE /FULL /CHARGE NO 3

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31/12/1231 December 2012 FULL ACCOUNTS MADE UP TO 31/12/12

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09/07/129 July 2012 AUTHORISED ALLOTMENT OF SHARES AND DEBENTURES

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09/07/129 July 2012 DISAPPLICATION OF PRE-EMPTION RIGHTS

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09/07/129 July 2012 COMPANY BUSINESS 29/06/2012

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01/06/121 June 2012 11/02/12 NO CHANGES

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23/05/1223 May 2012 04/05/12 STATEMENT OF CAPITAL GBP 6647800.66

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22/05/1222 May 2012 DIRECTOR'S CHANGE OF PARTICULARS / PERCY WILLIAM CECIL LOMAX / 27/03/2012

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31/12/1131 December 2011 FULL ACCOUNTS MADE UP TO 31/12/11

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06/07/116 July 2011 AUTHORISED ALLOTMENT OF SHARES AND DEBENTURES

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09/06/119 June 2011 01/03/11 STATEMENT OF CAPITAL GBP 294.93

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09/06/119 June 2011 01/03/11 STATEMENT OF CAPITAL GBP 470.84

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31/05/1131 May 2011 11/02/11 BULK LIST

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03/05/113 May 2011 01/03/11 STATEMENT OF CAPITAL GBP 370.28

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25/03/1125 March 2011 REGISTERED OFFICE CHANGED ON 25/03/2011 FROM, 73 WATLING STREET, LONDON, EC4M 9BJ

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25/03/1125 March 2011 DIRECTOR APPOINTED MR DAVID ALEXANDER HILL SCOTT

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25/03/1125 March 2011 DIRECTOR APPOINTED MICHAEL HICKS

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25/03/1125 March 2011 APPOINTMENT TERMINATED, DIRECTOR TIMOTHY SHILTON

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25/03/1125 March 2011 APPOINTMENT TERMINATED, DIRECTOR MARTIN SMALL

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25/03/1125 March 2011 APPOINTMENT TERMINATED, DIRECTOR PETER GARROD

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23/02/1123 February 2011 15/02/11 STATEMENT OF CAPITAL GBP 9116941.40

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23/02/1123 February 2011 18/02/11 STATEMENT OF CAPITAL GBP 6642438.06

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18/02/1118 February 2011 COMPANY NAME CHANGED REGEN THERAPEUTICS PLC CERTIFICATE ISSUED ON 18/02/11

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18/02/1118 February 2011 NOTICE OF CHANGE OF NAME NM01 - RESOLUTION

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17/02/1117 February 2011 REDUCTION OF ISSUED CAPITAL

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17/02/1117 February 2011 REDUCTION OF ISS CAPITAL AND MINUTE (OC)

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17/02/1117 February 2011 17/02/11 STATEMENT OF CAPITAL GBP 6612438.06

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31/01/1131 January 2011 DISAPPLICATION OF PRE-EMPTION RIGHTS

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28/01/1128 January 2011 17/01/11 STATEMENT OF CAPITAL GBP 1100

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31/12/1031 December 2010 GROUP OF COMPANIES' ACCOUNTS MADE UP TO 31/12/10

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18/10/1018 October 2010 29/09/10 STATEMENT OF CAPITAL GBP 833.33

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24/08/1024 August 2010 21/07/10 STATEMENT OF CAPITAL GBP 350

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12/07/1012 July 2010 30/06/10 STATEMENT OF CAPITAL GBP 500

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05/07/105 July 2010 AUTHORISED ALLOTMENT OF SHARES AND DEBENTURES

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05/07/105 July 2010 COMPANY BUSINESS 18/06/2010

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07/06/107 June 2010 20/05/10 STATEMENT OF CAPITAL GBP 350.0000

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07/06/107 June 2010 10/05/10 STATEMENT OF CAPITAL GBP 125

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07/06/107 June 2010 10/05/10 STATEMENT OF CAPITAL GBP 30

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07/06/107 June 2010 13/05/10 STATEMENT OF CAPITAL GBP 350.00

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07/06/107 June 2010 06/05/10 STATEMENT OF CAPITAL GBP 300

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26/04/1026 April 2010 11/02/10 BULK LIST

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20/04/1020 April 2010 29/03/10 STATEMENT OF CAPITAL GBP 500

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16/03/1016 March 2010 AUTHORISED ALLOTMENT OF SHARES AND DEBENTURES

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15/02/1015 February 2010 19/01/10 STATEMENT OF CAPITAL GBP 833333

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31/12/0931 December 2009 GROUP OF COMPANIES' ACCOUNTS MADE UP TO 31/12/09

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16/12/0916 December 2009 AUTHORISED ALLOTMENT OF SHARES AND DEBENTURES

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07/12/097 December 2009 04/11/09 STATEMENT OF CAPITAL GBP 250

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24/07/0924 July 2009 ADOPT ARTICLES 21/07/2009

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24/07/0924 July 2009 AUTHORISED ALLOTMENT OF SHARES AND DEBENTURES

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24/07/0924 July 2009 DISAPPLICATION OF PRE-EMPTION RIGHTS

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24/07/0924 July 2009 COMPANY BUSINESS 21/07/2009

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25/06/0925 June 2009 ARTICLES OF ASSOCIATION

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25/06/0925 June 2009 ALTER ARTICLES 06/10/2008

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25/06/0925 June 2009 AUTHORISED ALLOTMENT OF SHARES AND DEBENTURES

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25/06/0925 June 2009 RECLASSIFY SHARES 06/10/2008

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18/06/0918 June 2009 SECTION 519

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30/03/0930 March 2009 AUTHORISED ALLOTMENT OF SHARES AND DEBENTURES

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30/03/0930 March 2009 DISAPP PRE-EMPT RIGHTS 26/03/2009 AUTH ALLOT OF SECURITY 26/03/2009

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25/03/0925 March 2009 RETURN MADE UP TO 11/02/09; FULL LIST OF MEMBERS

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09/01/099 January 2009 AUTHORISED ALLOTMENT OF SHARES AND DEBENTURES

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09/01/099 January 2009 DISAPP PRE-EMPT RIGHTS 06/01/2009 AUTH ALLOT OF SECURITY 06/01/2009

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31/12/0831 December 2008 GROUP OF COMPANIES' ACCOUNTS MADE UP TO 31/12/08

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20/08/0820 August 2008 APPOINTMENT TERMINATED DIRECTOR KEITH CORBIN

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20/08/0820 August 2008 DIRECTOR RESIGNED KEITH CORBIN

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19/06/0819 June 2008 AUTHORISED ALLOTMENT OF SHARES AND DEBENTURES

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19/06/0819 June 2008 RE APPT DIRS AND AUDTR 03/06/2008 DISAPP PRE-EMPT RIGHTS 03/06/2008 AUTH ALLOT OF SECURITY 03/06/2008

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19/06/0819 June 2008 DISAPPLICATION OF PRE-EMPTION RIGHTS

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19/06/0819 June 2008 RE APPT DIRS AND AUDTR 03/06/2008

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11/04/0811 April 2008 RETURN MADE UP TO 11/02/08; BULK LIST AVAILABLE SEPARATELY

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11/04/0811 April 2008 RETURN MADE UP TO 11/02/08; BULK LIST AVAILABLE SEPARATELY;LOCATION OF REGISTER OF MEMBERS ADDRESS CHANGED; REGISTERED OFFICE CHANGED ON 11/04/08

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17/03/0817 March 2008 REGISTERED OFFICE CHANGED ON 17/03/2008 FROM, 8 BAKER STREET, LONDON, W1U 3LL

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17/03/0817 March 2008 REGISTERED OFFICE CHANGED ON 17/03/08 FROM: 8 BAKER STREET LONDON W1U 3LL

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31/12/0731 December 2007 GROUP OF COMPANIES' ACCOUNTS MADE UP TO 31/12/07

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30/11/0730 November 2007 CONSO 21/11/07

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30/11/0730 November 2007 AUTHORISED ALLOTMENT OF SHARES AND DEBENTURES

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30/11/0730 November 2007 DISAPPLICATION OF PRE-EMPTION RIGHTS

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30/11/0730 November 2007 RE CONSOLIDATION 20/11/07

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15/06/0715 June 2007 AUTHORISED ALLOTMENT OF SHARES AND DEBENTURES

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29/03/0729 March 2007 RETURN MADE UP TO 11/02/07; BULK LIST AVAILABLE SEPARATELY

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31/12/0631 December 2006 GROUP OF COMPANIES' ACCOUNTS MADE UP TO 31/12/06

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23/06/0623 June 2006 AUTHORISED ALLOTMENT OF SHARES AND DEBENTURES

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10/04/0610 April 2006 RETURN MADE UP TO 11/02/06; BULK LIST AVAILABLE SEPARATELY

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31/12/0531 December 2005 GROUP OF COMPANIES' ACCOUNTS MADE UP TO 31/12/05

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15/07/0515 July 2005 DIRECTOR RESIGNED

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10/05/0510 May 2005 ALTERATION TO MEMORANDUM AND ARTICLES

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22/03/0522 March 2005 NEW DIRECTOR APPOINTED

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16/03/0516 March 2005 RETURN MADE UP TO 11/02/05; BULK LIST AVAILABLE SEPARATELY

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17/01/0517 January 2005 SHARES AGREEMENT OTC

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31/12/0431 December 2004 GROUP OF COMPANIES' ACCOUNTS MADE UP TO 31/12/04

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29/10/0429 October 2004 DIRECTOR'S PARTICULARS CHANGED

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26/05/0426 May 2004 AUTHORISED ALLOTMENT OF SHARES AND DEBENTURES

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20/05/0420 May 2004 RETURN MADE UP TO 11/02/04; BULK LIST AVAILABLE SEPARATELY

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08/01/048 January 2004 AUDITOR'S RESIGNATION

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31/12/0331 December 2003 GROUP OF COMPANIES' ACCOUNTS MADE UP TO 31/12/03

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19/12/0319 December 2003 AUTHORISED ALLOTMENT OF SHARES AND DEBENTURES

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26/09/0326 September 2003 PARTICULARS OF MORTGAGE/CHARGE

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18/09/0318 September 2003 PARTICULARS OF MORTGAGE/CHARGE

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17/06/0317 June 2003 AUTHORISED ALLOTMENT OF SHARES AND DEBENTURES

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20/05/0320 May 2003 REGISTERED OFFICE CHANGED ON 20/05/03 FROM: 8 BAKER STREET, LONDON, W1M 1DA

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14/04/0314 April 2003 S-DIV 31/03/03

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14/04/0314 April 2003 ARTICLES OF ASSOCIATION

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14/04/0314 April 2003 ALTERATION TO MEMORANDUM AND ARTICLES

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14/04/0314 April 2003 AUTHORISED ALLOTMENT OF SHARES AND DEBENTURES

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14/04/0314 April 2003 VARYING SHARE RIGHTS AND NAMES

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14/04/0314 April 2003 SUB DIV SHARES 31/03/03

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28/02/0328 February 2003 RETURN MADE UP TO 11/02/03; BULK LIST AVAILABLE SEPARATELY

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28/02/0328 February 2003 RETURN MADE UP TO 11/02/03; BULK LIST AVAILABLE SEPARATELY;SECRETARY'S PARTICULARS CHANGED

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02/01/032 January 2003 NEW DIRECTOR APPOINTED

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31/12/0231 December 2002 GROUP OF COMPANIES' ACCOUNTS MADE UP TO 31/12/02

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24/12/0224 December 2002 AUTHORISED ALLOTMENT OF SHARES AND DEBENTURES

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24/12/0224 December 2002 SECT 95 10/12/02

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17/12/0217 December 2002 NEW DIRECTOR APPOINTED

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09/12/029 December 2002 DIRECTOR RESIGNED

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07/11/027 November 2002 PARTICULARS OF MORTGAGE/CHARGE

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06/11/026 November 2002 PARTICULARS OF MORTGAGE/CHARGE

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13/09/0213 September 2002 DIRECTOR RESIGNED

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13/09/0213 September 2002 DIRECTOR RESIGNED

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12/04/0212 April 2002 RETURN MADE UP TO 11/02/02; BULK LIST AVAILABLE SEPARATELY

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05/02/025 February 2002 AUTHORISED ALLOTMENT OF SHARES AND DEBENTURES

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21/01/0221 January 2002 DIRECTOR RESIGNED

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31/12/0131 December 2001 GROUP OF COMPANIES' ACCOUNTS MADE UP TO 31/12/01

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16/11/0116 November 2001 AUTHORISED ALLOTMENT OF SHARES AND DEBENTURES

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18/05/0118 May 2001 AUTHORITY- PURCHASE SHARES OTHER THAN FROM CAPITAL

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17/05/0117 May 2001 DIRECTOR RESIGNED

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13/04/0113 April 2001 SECRETARY RESIGNED

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27/03/0127 March 2001 RETURN MADE UP TO 11/02/01; BULK LIST AVAILABLE SEPARATELY

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14/03/0114 March 2001 NEW SECRETARY APPOINTED

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14/03/0114 March 2001 SECRETARY RESIGNED

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31/12/0031 December 2000 FULL GROUP ACCOUNTS MADE UP TO 31/12/00

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09/05/009 May 2000 RETURN MADE UP TO 11/02/00; BULK LIST AVAILABLE SEPARATELY

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27/03/0027 March 2000 AUTH. ALLOTMENT OF SHARES AND DEBENTURES 22/03/00

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10/03/0010 March 2000 NEW DIRECTOR APPOINTED

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29/02/0029 February 2000 PROSPECTUS

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21/02/0021 February 2000 NEW DIRECTOR APPOINTED

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31/12/9931 December 1999 FULL GROUP ACCOUNTS MADE UP TO 31/12/99

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22/07/9922 July 1999 DELIVERY EXT'D 3 MTH 31/12/98

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29/06/9929 June 1999 NEW DIRECTOR APPOINTED

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21/06/9921 June 1999 DIRECTOR RESIGNED

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07/06/997 June 1999 NEW SECRETARY APPOINTED

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07/06/997 June 1999 SECRETARY RESIGNED;DIRECTOR RESIGNED

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02/05/992 May 1999 REGISTERED OFFICE CHANGED ON 02/05/99 FROM: CLIFFORDS INN, FETTER LANE, LONDON, EC4A 1AS

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02/05/992 May 1999 REGISTERED OFFICE CHANGED ON 02/05/99 FROM: G OFFICE CHANGED 02/05/99 CLIFFORDS INN FETTER LANE LONDON EC4A 1AS

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28/04/9928 April 1999 LOCATION OF REGISTER OF MEMBERS

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28/04/9928 April 1999 RETURN MADE UP TO 11/02/99; BULK LIST AVAILABLE SEPARATELY

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16/02/9916 February 1999 NEW DIRECTOR APPOINTED

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08/02/998 February 1999 NEW DIRECTOR APPOINTED

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08/02/998 February 1999 NEW DIRECTOR APPOINTED

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31/12/9831 December 1998 FULL GROUP ACCOUNTS MADE UP TO 31/12/98

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22/12/9822 December 1998 SHARES AGREEMENT OTC

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18/11/9818 November 1998 APPLICATION COMMENCE BUSINESS

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18/11/9818 November 1998 AUTHORISATION TO COMMENCE BUSINESS AND BORROW

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18/11/9818 November 1998 PROSPECTUS

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09/10/989 October 1998 PROSPECTUS

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11/08/9811 August 1998 NC INC ALREADY ADJUSTED 17/07/98

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11/08/9811 August 1998 AUTH. ALLOTMENT OF SHARES AND DEBENTURES 17/07/98

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11/08/9811 August 1998 SUB-DIV SHARES 17/07/98

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11/08/9811 August 1998 DISAPPLICATION OF PRE-EMPTION RIGHTS 17/07/98

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10/08/9810 August 1998 MEMORANDUM OF ASSOCIATION ARTICLES OF ASSOCIATION

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06/08/986 August 1998 COMPANY NAME CHANGED REGEN THERAPEUTICS PLC CERTIFICATE ISSUED ON 07/08/98

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24/07/9824 July 1998 S-DIV 17/05/98

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24/07/9824 July 1998 £ NC 50000/35000000 17/07/98

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24/07/9824 July 1998 NC INC ALREADY ADJUSTED 17/07/98

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24/07/9824 July 1998 AUTH. ALLOTMENT OF SHARES AND DEBENTURES 17/07/98

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24/07/9824 July 1998 ALTER MEM AND ARTS 17/07/98

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20/07/9820 July 1998 NEW DIRECTOR APPOINTED

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03/07/983 July 1998 NEW DIRECTOR APPOINTED

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24/06/9824 June 1998 ACC. REF. DATE SHORTENED FROM 28/02/99 TO 31/12/98

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24/06/9824 June 1998 REGISTERED OFFICE CHANGED ON 24/06/98 FROM: 10-11 NEW STREET, LONDON, EC2M 4TP

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24/06/9824 June 1998 REGISTERED OFFICE CHANGED ON 24/06/98 FROM: G OFFICE CHANGED 24/06/98 10-11 NEW STREET LONDON EC2M 4TP

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24/06/9824 June 1998 NEW DIRECTOR APPOINTED

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05/06/985 June 1998 COMPANY NAME CHANGED BIGBOOM PLC CERTIFICATE ISSUED ON 08/06/98

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22/04/9822 April 1998 REGISTERED OFFICE CHANGED ON 22/04/98 FROM: 120 EAST ROAD, LONDON, N1 6AA

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22/04/9822 April 1998 REGISTERED OFFICE CHANGED ON 22/04/98 FROM: G OFFICE CHANGED 22/04/98 120 EAST ROAD LONDON N1 6AA

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22/04/9822 April 1998 NEW SECRETARY APPOINTED;NEW DIRECTOR APPOINTED

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22/04/9822 April 1998 NEW DIRECTOR APPOINTED

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22/04/9822 April 1998 SECRETARY RESIGNED;DIRECTOR RESIGNED

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22/04/9822 April 1998 DIRECTOR RESIGNED

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10/03/9810 March 1998 ALTER MEM AND ARTS 05/03/98

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11/02/9811 February 1998 INCORPORATION DOCUMENTS CERTIFICATE OF INCORPORATION STATEMENT OF DIRECTORS & REGISTERED OFFICE DECLARATION OF COMPLIANCE MEMORANDUM OF ASSOCIATION ARTICLES OF ASSOCIATION

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