HELPERBY THERAPEUTICS LIMITED

Company number 04390014 ·

Active

Executive summary

Helperby Therapeutics Limited operates in the challenging UK antimicrobial development sub-sector, where extended pre-revenue periods are industry norms but the company's 22-year track record without commercial traction and critically thin capitalisation (£17,591 cash, £26.1M accumulated losses) place it well below typical sector benchmarks for R&D-stage biotechs. While the macro policy environment for AMR-focused companies is improving and the drug repurposing approach offers theoretical advantages, the company's extreme dependence on parent entity funding, worsening loss trajectory, and negligible asset base suggest it functions primarily as an IP-holding vehicle within the Helperby Therapeutics Group rather than as a commercially viable standalone enterprise. Survival and any potential value realisation remain entirely contingent on continued group-level financial support and successful progression of the IP portfolio toward partnership or licensing outcomes.

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Shareholders' funds

-£26,131,377

Balance sheet as at 2024-12-31

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Overview

Company type
Private Limited Company
Incorporated
2002-03-08
Employees
3 (2024 accounts · was 2 in 2023)
Registered office
C/O Dragon Argent Limited, 3 More London Riverside, London, United Kingdom, SE1 2RE
Postcode
SE1 2RE
Capital
137,116 GBP
Accounts category
Small
Charges
0 outstanding

Accounts

Last made up to
2024-12-31
Next due by
2026-09-30
Financial year end
30 December

Confirmation statement

Last statement dated
2026-03-11
Next due by
2027-03-25
View filing history →

Nature of business (SIC)

  • 82990 Other business support service activities not elsewhere classified

Officers 3 current · 16 resigned

Appointed 2019-07-30
DA SECRETARIAL LIMITED Corporate Secretary · corporate
Appointed 2019-07-30
Appointed 2002-03-08

View all officers and resignations →

Group structure 1 subsidiary

Controlled by HELPERBY THERAPEUTICS GROUP LIMITED — since 2016-04-06

From persons-with-significant-control filings on the public register.

Data protection registration

Registered with the ICO as a data protection fee payer — ZA813852 (Tier 1), registered since 2020.

Information Commissioner's Office register of fee payers, licensed under the Open Government Licence.

Contact details

Website
helperby.com
Phone
+44 2072054624

Helperby has nearly 20 years experience designing combinations of antimicrobials in order to rejuvenate old drugs and to find more uses for drugs that already exist on the market.

Previous company names

NameDate changed
BIOTHERAPIES LIMITED2003-02-04

Previous registered addresses 5

AddressChanged on
25 MANCHESTER SQUARE, LONDON, W1U 3PY2014-01-15
20-24 PARK STREET, SELBY, NORTH YORKSHIRE, YO8 4PW2010-02-08
135 GLOUCESTER ROAD, LONDON, SW7 4TH2003-02-09
CHESHAM HOUSE, 150 REGENT STREET, LONDON, W1R 5FA2002-11-25
OCTAGON HOUSE, FIR ROAD, BRAMHALL, STOCKPORT, CHESHIRE SK7 2NP2002-03-21

Among its peers

Among the biggest employers

of 1,237 similar companies in SE, with 3 staff. Among the oldest 25% of its local peers.

203 companies are registered at this postcode →

Competitors London

This company ranks 2027 among other business support service activities not elsewhere classified in London.

Full league table →

The class of 2002

28%

of the 9,102 companies in this sector incorporated in 2002 are still active today; 71% have since been dissolved.

A fact about the year, not a forecast for this company.

Survival rates for every incorporation year →